Choosing the right toothpaste can make a big difference in your daily dental routine. Whether you’re looking for something to whiten your teeth, fight cavities, or freshen your breath, Amazon offers a wide selection to suit every need. We’ve rounded up some of the best toothpaste brands you can buy online—convenient, highly rated, and often available with fast Prime shipping!
1. Crest 3D White Brilliance Toothpaste
If you’re dreaming of a whiter smile, this one's a fan favorite. The Crest 3D White Brilliance formula helps remove up to 95% of surface stains in just 3 days. It also has a refreshing mint flavor and fluoride to protect against cavities.
Why we love it:
Excellent for stain removal
Safe for daily use
Pairs well with Crest whitening strips for even better results
2. Sensodyne Pronamel Gentle Whitening
For those with sensitive teeth, Sensodyne Pronamel offers gentle care without compromising on whitening. It strengthens enamel and protects against acid erosion while keeping your smile bright.
Why it’s great:
Trusted by dentists worldwide
Strengthens enamel over time
Gentle on teeth and gums
3. Tom’s of Maine Natural Fluoride Toothpaste
Prefer a natural option? Tom’s of Maine offers a fluoride toothpaste made with naturally derived ingredients. It’s a great pick for eco-conscious shoppers who still want reliable cavity protection.
Highlights:
No artificial flavors, colors, or preservatives
Cruelty-free & environmentally friendly
Available in peppermint, fennel, and other unique flavors
4. Colgate Optic White Advanced
A reliable household name, Colgate Optic White Advanced uses hydrogen peroxide for deep whitening, helping you achieve a noticeably brighter smile in just a few weeks.
Why it stands out:
Affordable and widely trusted
Works well for coffee, tea, and wine stains
Powerful but not overly harsh
Final Thoughts
The best toothpaste for you depends on your oral care goals—whether that’s sensitivity relief, whitening power, or natural ingredients. These Amazon best-sellers are not only highly rated, but also frequently discounted and easy to have shipped right to your door.
💡 Tip: Don’t forget to check Amazon bundles or subscribe-and-save deals for extra savings!